givinostat drug Ask the Chatbot a Question Ask the Chatbot a Question Written by Kara Rogers Kara Rogers is the senior editor of biomedical sciences at Encyclopædia Britannica, where she oversees a range of content from medicine and genetics to microorganisms. She joined Britannica in 2006 and... Kara Rogers Fact-checked by The Editors of Encyclopaedia Britannica Encyclopaedia Britannica's editors oversee subject areas in which they have extensive knowledge, whether from years of experience gained by working on that content or via study for an advanced degree. They write new content and verify and edit content received from contributors. The Editors of Encyclopaedia Britannica Last Updated: Nov 20, 2024 • Article History Table of Contents Table of Contents Ask the Chatbot a Question givinostat, drug used to help slow the advance of Duchenne muscular dystrophy (DMD), a genetic condition characterized by progressive muscle degeneration and weakness. Givinostat is the first nonsteroidal medication available to treat all genetic variants of DMD. The drug was approved in 2024 by the U.S. Food and Drug Administration (FDA) for the treatment of DMD; it is marketed under the trade name Duvyzat. Givinostat belongs to a class of drugs known as histone deacetylase (HDAC) inhibitors. HDAC inhibitors gained attention in the early 2000s for their ability to modify gene expression, which could be beneficial for treating cancer, inflammation, ...(100 of 454 words)

　　Access the full article Help support true facts by becoming a member. Subscribe today!