omalizumab drug Ask the Chatbot a Question Ask the Chatbot a Question Written by Kara Rogers Kara Rogers is the senior editor of biomedical sciences at Encyclopædia Britannica, where she oversees a range of content from medicine and genetics to microorganisms. She joined Britannica in 2006 and... Kara Rogers Fact-checked by The Editors of Encyclopaedia Britannica Encyclopaedia Britannica's editors oversee subject areas in which they have extensive knowledge, whether from years of experience gained by working on that content or via study for an advanced degree. They write new content and verify and edit content received from contributors. The Editors of Encyclopaedia Britannica Last Updated: Nov 18, 2024 • Article History Table of Contents Table of Contents Ask the Chatbot a Question { "@context": "https://schema.org", "@type": "FAQPage", "mainEntity": [ { "@type" : "Question", "name" : " What conditions is omalizumab used to treat? ", "acceptedAnswer" : { "@type" : "Answer", "text" : "Omalizumab is used to treat moderate to severe allergic asthma, chronic spontaneous urticaria (hives), and nasal polyps. It continues to be investigated for additional applications, including its potential use for atopic dermatitis and food allergies." } } , { "@type" : "Question", "name" : " How does omalizumab work? ", "acceptedAnswer" : { "@type" : "Answer", "text" : "Omalizumab works by blocking the effects of the antibody immunoglobulin E (IgE), preventing it from binding to immune cells and inhibiting the release of inflammatory molecules. These effects ultimately help mitigate the severity of allergic reactions." } } , { "@type" : "Question", "name" : " When was omalizumab first approved by the FDA? ", "acceptedAnswer" : { "@type" : "Answer", "text" : "Omalizumab was first approved by the U.S. Food and Drug Administration (FDA) in 2003 for individuals with severe allergic asthma who do not respond well to inhaled corticosteroids." } } , { "@type" : "Question", "name" : " What are common side effects of omalizumab? ", "acceptedAnswer" : { "@type" : "Answer", "text" : "Common side effects of omalizumab include headache, fatigue, joint and muscle pain, pain at the injection site, and symptoms of upper respiratory tract infection." } } ] } Top Questions What conditions is omalizumab used to treat? Omalizumab is used to treat moderate to severe allergic asthma, chronic spontaneous urticaria (hives), and nasal polyps. It continues to be investigated for additional applications, including its potential use for atopic dermatitis and food allergies.

　　How does omalizumab work? Omalizumab works by blocking the effects of the antibody immunoglobulin E (IgE), preventing it from binding to immune cells and inhibiting the release of inflammatory molecules. These effects ultimately help mitigate the severity of allergic reactions.

　　When was omalizumab first approved by the FDA? Omalizumab was first approved by the U.S. Food and Drug Administration (FDA) in 2003 for individuals with severe allergic asthma who do not respond well to inhaled corticosteroids.

　　What are common side effects of omalizumab? Common side effects of omalizumab include headache, fatigue, joint and muscle pain, pain at the injection site, and symptoms of upper respiratory tract infection.

　　omalizumab, monoclonal antibody used in the treatment of moderate to severe allergic asthma, chronic spontaneous urticaria (hives), and nasal polyps. Omalizumab is the first monoclonal antibody designed to specifically block the effects of the antibody immunoglobulin E (IgE), which plays a key role in allergic reactions. The drug was developed in the 1990s by the pharmaceutical companies Genentech, Tanox, and Novartis and is marketed under the trade name Xolair. Research in the 1970s and ’80s highlighted the role of IgE antibodies in allergic reactions, particularly in conditions such as asthma and hives. In response to exposure to certain allergens, IgE ...(100 of 833 words)

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